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Genetic predisposition plays a significant role in tumorigenesis and cancer prevention .

基因的遗传多型性对於肿瘤的发生和预防扮演一个重要的角色。

Characterize aurkc transcription and its function in tumorigenesis .

探讨aurkc基因转录及参与细胞癌化的功能扮演。

Oncogenic mutations initiate tumorigenesis , but angiogenesis is necessary for expansion of tumor mass .

癌基因突变引起肿瘤形成，而血管生成则是肿瘤扩大所必需的。

However , the regulation and etiology of as in human tumorigenesis is not well understood .

但是，人类肿瘤发生的产生和调节机制目前还没有很好的了解。

The tumor microenvironment is known to play an important role in tumorigenesis .

众所周知。肿瘤的微环境对肿瘤的发生起着重要作用。