易混淆的单词： Cisplatin

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When pidd levels are artificially increased in human lung cancer cells , they become more resistant to cisplatin .

当pidd水平在肺癌细胞人为增加时，它们对顺铂耐药性增强。

After four doses of cisplatin , mice with normal p53 developed resistance to the drug , and tumors started growing faster .

在四个顺铂剂量之后，有正常p53的小鼠获得了药物的耐药性，肿瘤开始加速生长。

Now , mit cancer biologists have shown how that resistance arises , a finding that could help researchers design new drugs that overcome cisplatin resistance .

现在，mit癌症生物学家已经展现了耐药性是如何增加的，这项发现可能帮助研究员设计可以克服顺铂耐药性的新药。

The researchers found that cisplatin was effective against lung tumors in both sets of mice , though it was more potent in mice that still had functional p53 .

研究员发现顺铂可以有效对抗这两种小鼠（kras和p53基因突变组）的肺癌，即使它在那些仍旧有有功能的p53的小鼠更有效。

Cisplatin and other platinum-based cancer drugs destroy tumor cells by binding to dna strands , interfering with dna replication .

顺铂和其他以铂为基础的癌症药物通过靶定dna链，干扰dna复制而破坏肿瘤细胞。