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Soon after , people began to experiment with more controversial , human-made additives - first , the anti-malarial medication chloroquine , and later , dec.

很快，人们开始尝试更多有争议的人工合成物质，首先是防治疟疾的氯喹，然后是dec。

Effects of chloroquine on incorporation of labelled compound and on cotents of amino acids in plasmodium berghei .

氯喹对伯氏疟原虫摄取次黄嘌呤、甲硫氨酸、精氨酸及其氨基酸组成的影响。

Change in chloroquine resistance of plasmodium falciparum in hainan by in vitro test .

体外测定海南省恶性疟原虫对氯喹抗性的变化。

This is no mere theoretical concern : malaria is now highly resistant to a previous wonder drug , chloroquine , and researchers have detected signs of resistance to artemisinin in areas where monotherapies are widely used .

这不仅仅是理论上的担忧：现在疟疾对以前的一种特效药氯喹已具有极高的抗药性，而且研究人员已经在广泛使用单一药物疗法的地区发现了对青蒿素产生抗药性的迹象。

Most researchers believe that parasite resistance to chloroquine and antifolate-two drugs that were once used to treat malaria-also arose in western cambodia and then spread throughout southeast asia into africa , rapidly reducing the ability of those drugs to treat infections .

大多数研究人员认为，疟原虫对氯喹和叶酸拮抗剂的抗药性这两种药曾用于治疗疟疾也首先出现在柬埔寨西部，然后通过东南亚扩散到非洲，快速地降低了这些药物治疗感染的能力。