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Investigation of the effects of naloxone plus Aminophyline Therapy on primary apnea of preterm infants

纳络酮与氨茶碱交替使用治疗早产儿原发性呼吸暂停的疗效观察

Spleen lymphocytes from mice treated with aminophyline showed significant weaker GVHR than that treated with normal saline , suggesting that aminophylline might induce suppressor cells in vivo .

给小鼠胃饲氨茶碱，其脾脏淋巴细胞所引起的GVHR也较胃饲生理盐水者为弱，提示氨茶碱在体内也可诱导具有免疫抑制作用的细胞。

Methods Review and retrospectively analyze the method of combined therapy on 45 cases of apnea of very low birth weight infant in our hospital nearly 4 years , drug treatment with aminophyline and naloxone .

方法对近4年我院收治的极低出生体重儿合并呼吸暂停45例的综合治疗进行回顾性总结，其中药物治疗用氨茶碱和纳络酮。

Conclusion Aminophyline could inhibit the inflammation of asthmatic airway by reducing the expression of TRAIL in rat lung and promoting the apoptosis of T-lymphocytes in asthmatic rat airway .

结论氨茶碱可能通过抑制肺组织TRAIL的表达来抑制TRAIL的促炎作用，同时还可以通过促进哮喘大鼠气道的T淋巴细胞凋亡发挥抗炎作用。

Methods : ① Guinea pigs of asthma models were divided into 4 groups , treatment group with herbal penetration along channel , control group , aminophyline injection group and aminophyline penetration group . After one week of treatment , the latent period of asthmatic attack was recorded .

方法：①采用哮喘造模豚鼠分为中药敷贴组、模型对照组、氨茶碱注射组、氨茶碱敷贴组，治疗1周后记录哮喘潜伏时间；